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PO Box 16122 Collins Street West Victoria, Australia

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ABOUT THE LAB

Lifelong maintenance of mitochondrial networks in long-lived cells

Mitochondria have a remarkable ability to tailor their morphology, function, and behavior according to the specialized needs of the cell they inhabit. These differences translate to functional and behavioral specializations, which are critical for cells to fulfill their dedicated functions. In our laboratory, we aim to define how cells, particularly neurons and oocytes, establish their mitochondrial populations and maintain their health throughout the cells’ lifetime.

ABOUT THE LAB

At the forefront of mitochondria research

We are dedicated to advancing the understanding of mitochondria, the powerhouse of the cell, and their critical role in human health. Our multidisciplinary team of scientists explores the intricate functions of mitochondria in cellular energy production, aging, and disease.

OUR TEAM

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OUR WORKS

Publications

Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and the translation of nuclear-encoded proteins

Cardanho-Ramos, Carlos et al. Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and the translation of nuclear-encoded proteins. iScience, Volume 27, Issue 4, 109136

Publications

Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan

Bomba-Warczak E., Velez K., Zhou L., Guillermier C., Edassery S., Steinhauser M., Savas J., Duncan F. Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan. Elife. (accepted 10/16/2023; manuscript available upon request)

Highlight Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan

Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3

Ramirez, Miguel A. et al. Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3. iScience, Volume 25, Issue 8, 104803\

Publications
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